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In addition, our findings suggest that chelating bioreactive iron within aberrant erythrocytes might be a potential therapy strategy

Artif Cells Nanomed Biotechnol 52:5968

The Science Says: Works acutely but tolerance builds quickly

(2011) used the histone deacetylase inhibitor depispeptide to reverse DNA hypermethylation and alter the histone modification pattern at GSTP1 promoter, including a reduction of H3K9me2/3 and H3K27me2/3 and an increase of H3K18Ac, thereby inducing GSTP1 mRNA re-expression
