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With aging, muscle stem cell function gradually declines, showing reduced proliferation and fusion, leading to impaired regeneration-one of the key mechanisms underlying sarcopenia.In vitro experiments confirm that 5-amino-1mq significantly enhances the proliferation and fusion of muscle stem cells from aged mice

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Further research is needed to develop new tools for diagnosing painful discs that require cell therapy, to develop alternative pathways to eliminate nociceptors growing in painful discs, to further understand the fate and action mechanism of transplanted cells, and to restore the mechanical environment of degenerate discs, so that cell therapy finally moves from the laboratory to the clinic
