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Description
After absorption, DHFR sequentially reduces monoglutamate to DHF and then to 5-methyl-THF

Design, synthesis, and application of azabicyclo[X.Y.O]alkanone amino acids as constrained dipeptide surrogates and peptide mimics
Mease P, Arnold LM, Bennett R, et al

Preliminary report: cyclosporin in treatment of severe active ulcerative colitis
