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In Barth syndrome patients, 48 weeks of SS-31 treatment produced significant improvements in the 6-minute walk test, symptom scores, and cardiac physiology

As referred to earlier, the hallmarks of Alzheimers disease include tau and amyloid deposition and in one study tau increase of SOD1 expression, which in animal studies, the wild-type SOD1 gene expression was found to be protective against NDG

The periplasmic gate, in contrast, likely facilitates the alignment and entry of cargo into the secretin chamber