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Pre-existing conditions like peripheral neuropathy or heightened skin reactivity may amplify sensations, though serious reactions remain uncommon in clinical settings

Chromatographic analysis was performed using the Shimadzu high-performance liquid chromatography (HPLC) system composed of two quaternary pumps, an autosampler (model 20ACHT), and a diode array detector (DAD) (model SPD-M20A) and a C18 (ODS) reverse phase (150 mm 4.5 mm) column

Increased oxidative stress is mainly regulated by the activation of Nrf2, a transcription factor with anti-inflammatory and antioxidant properties [39]
Larsen KE, Schmitz Y, Troyer MD, Mosharov E, Dietrich P, Quazi AZ, et al
