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[DOI] [PMC free article] [PubMed] [Google Scholar] 183.Yu E., Calvert P.A., Mercer J.R., Harrison J., Baker L., Figg N.L., Kumar S., Wang J.C., Hurst L.A., Obaid D.R., et al

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A significant limitation of permeation enhancers is the potential for local mucosal irritation, impaired ciliary function, and epithelial disruption, particularly when surfactant-type enhancers are utilised at elevated concentrations or with prolonged exposure (Maher et al., 2019

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