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Intermittent claudication is a warning of systemic atherosclerosis and is considered an independent risk factor for cardiovascular morbidity and mortality [48]
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Catching up on sleep, such as by sleeping late on weekends, appears to mitigate, though may not completely reverse, some of the negative health effects of sleep loss

Research has also indicated that L-carnitine plays a role in boosting the number of testosterone receptors, enhancing nitric oxide production, and may facilitate the action of the anabolic hormone IGF-1
