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Description
It is relatively unreactive, but upon interaction with superoxide, it may result in peroxynitrite (ONOO), which is associated with cellular injury and inflammation
The mechanism is not fully established, but the preservative may offer a mild stabilizing effect on certain peptide bonds

Mol Oncol (2017) 11(7):80523

Patients with active deficiency or pernicious anemia often need weekly injections for the first 4 to 6 weeks, then monthly maintenance, while those using B12 for energy support usually settle into a monthly cadence