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Description
It has been documented that an electrophilic metabolite of acetaminophen N-acetyl-p-benzoquinone imine (NAPQI) reacts with CysSSH or GSSH forming mixed disulfides NAPQIH 2 -SSCys or NAPQIH 2 -SSG, respectively [73]
Most people tolerate glutathione IV well when it is administered by a trained professional using quality-controlled formulations
Normalized were malondialdehyde (MDA)- and NO-levels in the liver, next to Western blot of NOS2 and NOS3 in the liver tissue, and decreased IL-6, TNF-, and IL-1 levels in liver tissues
doi: 10.1161/01.res.59.3.297
