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Regulation on citrate influx and metabolism through inhibiting SLC13A5 and ACLY: A novel mechanism mediating the therapeutic effects of Curcumin on NAFLD

The accelerated drug approval introduced by the FDA in 2024 was probably made possible by growing acceptance of precision medicine and genetic screening in targeted therapies, for instance, those for non-small-cell lung cancer and pancreatic adenocarcinoma, by approving zenocutuzumab-zbco (brand name Bizengri , and for transthyretin-mediated amyloidosis causing cardiomyopathy and heart failure, by approving acoramidis (brand names Attruby and Beyonttra, The P4 medicine paradigm continues to demonstrate its value across chronic diseases, even as attention increasingly shifts toward rare disorders

Exploring Candida auris in its habitat

Nat Rev Nephrol 20:118 Gu J, Chen Y, Tong L, Wang X, Yu D, Wu H (2020) Astaxanthin-loaded polymer-lipid hybrid nanoparticles (ATX-LPN): assessment of potential otoprotective effects