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Finally, the FlowJo software (Version 10.4, BD Biosciences, USA) was used to analyze the result with a gating strategy shown in Supplementary Fig

TC: Conceptualization, Writing review & editing

216 The CS resulting from the significant release of IL-1 and TNF has the potential to induce myocardial suppression, vasodilation, tissue injury, and mortality through the upregulation of nitric oxide synthesis, myocardial cell contraction, facilitation of immune cell adhesion and activation, and initiation of exogenous coagulation pathways

Current evidence summary In 11 lactating women given 5 mg subcutaneous tirzepatide, 95.9 percent of milk samples showed undetectable levels