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82 In vitro studies revealed that inhibitors of DNMT1 (5-azacytidine, procainamide or hydralazine) could induce hypomethylation with subsequent autoreactivity in naive T cells, 83 providing strong evidence for causation in SLE

Prodrugs can be chemically modified to improve their solubility and stability, which are critical factors for drug delivery and efficacy

The effect of near-UV light on Na-K-ATPase of the rat lens

In addition to vasoprotection, oral administration of quercetin-3- O -gentiobiose (2575 mg/kg) once daily for two weeks considerably improved the endurance capability of rats against fatigue, decreased serum blood urea nitrogen (BUN) and lactic acid levels, enhanced the activities of antioxidant enzymes (SOD, glutathione peroxidase) and attenuated inflammatory cytokine levels (MCP-1, IL-6 and TNF-)