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Convergent mechanismsoxidative stress, mitochondrial insufficiency, cellular senescence, immunosenescence with low-grade inflammation, and disrupted cholinergic/catecholaminergic signalingjointly depress tear volume and alter composition

Once in the brain, ALC supports the production and activity of acetylcholine, a neurotransmitter involved in memory, focus, and overall cognitive function.* It also supports mitochondrial function in brain cells, contributing to the same energy production pathway that CoQ10 supports throughout the rest of the body.*

Metformin is generally described as safe, effective and cheap, but one notable harm associated with its use is vitamin B12 deficiency

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