Vitamin B12 (Hydroxocobalamin) Injection
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Description
In the intrinsic pathway, mitochondrial membrane permeabilization allows cytochrome c to enter the cytosol, forming the apoptosome with APAF-1 and caspase-9, which then activates caspase-3, leading to nuclear fragmentation, protein degradation, and chromatin condensation [32]
Cell 18 , 189200 (2007)
2009;296:C12581270
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