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Ferroptosis in tumor suppression and immune functions The first evidence linking ferroptosis and tumors was the discovery that p53, a well-known tumor suppressor, sensitizes tumor cells to ferroptosis by inhibiting the expression of SLC7A11, a key component of the cystine/glutamate antiporter that mediates cystine transport and represses ROS-induced ferroptosis [8, 206208]

However, a large population-based study in Denmark found no correlation between infection with the helminth Enterobius vermicularis and the incidence of T1D (106)

In: Feingold KR, Anawalt B, Boyce A, et al., editors

Immune system reinforcement