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Unlike some genetic or high-throughput platforms, they do not require live cell screening and can handle proteins that are difficult to express in other systems

PLoS ONE 2015
Of note, APP can also be cleaved via the non-amyloid pathway, a process mediated by and secretase, which do not produce A (Musiek et al., 2021)

These benefits arise from complex interactions involving physiological, psychological, and neurobiological mechanisms
