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The selective blockade of metabotropic glutamate receptor-5 attenuates fat accumulation in an in vitro model of benign steatosis

Oxidative stress in the liver is regulated by both enzymatic and nonenzymatic antioxidant systems [33]
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Another study found that IFN- downregulates melanin regulators (DCT, KITLG, FZD5), leading to decreased melanin production in melanocytes, and promotes lipid peroxidation (ROS) and ferroptosis in primary melanocytes derived from patients
