glutathione gbm6 patient derived xenograft Combined inhibition of de novo and nucleotide biosynthesis is synthetically lethal in glioblastoma: Cell Reports Combination Treatment with the GSK-3

Kanner J., and Lapidot T

Introduction Peripheral neuropathy (PN), a condition characterized by damage to the peripheral nerves, is a major clinical concern due to its prevalence and significant impact on patients quality of life [1,2,3]

Additionally, puerarin was reported to directly benefit diabetes mellitus and a series of complications by decreasing blood glucose levels, improving insulin resistance, protecting islets, inhibiting inflammation, decreasing oxidative stress, and inhibiting Maillard reaction and advanced glycation end products (AGEs) formation [281]

The decrease of lymphocyte interferon gamma expression during aging is one of the main mechanisms leading to the immunodeficiency