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Even though different RCDs are considered individual and independent cell death modes for classification purposes, interconnectivity and extensive crosstalk on the basis of the shared molecular signaling network, redundancy, feedback, and backup function are well documented [10]

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Abbreviations H 2 O 2 : Hydrogen peroxide GST: Glutathione S-Transferase GSH: Reduced Glutathione ROS: Reactive oxygen species O: Superoxide anion FSH: Follicle-stimulating hormone CAT: Catalase LH: Luteinising hormone TCA: Thiobarbituric acid CDNB: 1-chloro-2,4-dinitrobenzene TBARS: Thiobarbituric acid reactive substances MSG: Monosodium glutamate LPS: Lipopolysaccharides DTNB: 5,5-dithiobis (2-nitrobenzoic acid) SOD: Superoxide dismutase References Huhtaniemi I, Toppari J

In the present study, a well established rat model of periodontitis was utilized, which involves a ligature around the cervix of the mandibular first molar tooth (9, 10)