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Description
Mechanistically, permeation enhancement is typically achieved through transient modulation of epithelial tight junctions to increase paracellular transport, alteration of membrane organisation to facilitate transcellular diffusion, and may also influence local mucus-drug interactions or enzymatic stability depending on excipient chemistry and exposure profile (Maher et al., 2019)
Some patients in studies have preferred using high dose oral
Note that these have implemented as a crucial diagnostic tool in ophthalmology
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