glutathione interactions with drugs Glutathione-Mediated Conjugation of Anticancer Drugs: An Overview of Reaction Mechanisms and Biological Significance for Drug Detoxification and Bioactivation Glutathione metabolism and glutathione-dependent cellular
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To be specific, these two drugs can directly suppress the formation of BRAF:CRAF heterodimers normally observed in RAS -mutated cells receiving the treatment of RAF inhibitors, meanwhile maintaining the binding affinity for the dimer partner
Inhibiting the effect of this gene on GPX4 degradation could alleviate this condition
doi: 10.1007/s00535-021-01788-x 38
