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Free radicals may affect skin hydration by reducing elastin and collagen of the skin that may result in wrinkle formation

IRBM-Z-2 is a non-competitive, orally active Zika virus (ZIKV) NS2B-NS3 protease inhibitor, with IC50 values of 0.04 M and 3.1 M against the wild-type and I156T mutant strains, respectively
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