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Taken together, this suggests that beta-amyloid formation is inhibited in PD, but that tau aggregation, and its associated cognitive deficits 226 , are present even in PD patients with low beta-amyloid burden 220,221

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P442 Clinical outcomes of isavuconazole versus voriconazole for the primary treatment of invasive aspergillosis: subset analysis of Indian data from SECURE trial P Kundu, S Kamat, A Mane Pfizer Limited, Medical Affairs, Mumbai, India Introduction: The SECURE trial was designed to compare the safety and efficacy of Isavuconazole (A) versus Voriconazole (V) for primary treatment of invasive mould disease caused by Aspergillus and other filamentous fungi