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10 mg/kg) to DMBA-administered rats suppressed mammary carcinogenesis, and this correlated with declines in serum cholesterol, low-density lipoprotein (LDL)-cholesterol, and HMG CoA reductase protein [65]

Nature 597 , 420425 (2021)

However, no differences were observed in the percentage of distance traveled in the center zone, a common measure of anxiety-like behavior, indicating that HDAC9 deletion in CA1 does not affect anxiety levels (Fig

Under neuroinflammatory conditions, dysfunctional mitochondria release ROS and damage-associated molecular patterns (DAMPs) (53), activating microglia and astrocytes, and triggering the release of pro-inflammatory cytokines and chemokines (54), thereby exacerbating the damage