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Description
R., & Park, G
preclinical, not approved
Regulatory status As of June 2026, tesamorelin is FDA-approved only for HIV-associated lipodystrophy (EGRIFTA WR / EGRIFTA SV)
In murine studies, deletion of the IGF-1R in skeletal muscle resulted in glucose intolerance issues ultimately leading to T2D at an early age, because, although they express insulin receptors, they cannot form hybrid or IGF-1 receptors [162]
