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Equally important is the development of biomarkers reflecting iron-handling capacity, lipid oxidative signatures, or ferroptosis-associated cytokine patterns to guide patient stratification and optimize therapy

Overall, resveratrol exerts multi-faceted anti-cancer effects by modulating tumor immunity (e.g., boosting cytotoxic T cells and NK cells), reversing drug resistance (via down-regulating EGFR and P-gp), inducing autophagy and ferroptosis, and arresting cell cycle progression while promoting apoptosis

[38] [39] A GST-tag is often used to separate and purify proteins that contain the GST-fusion protein

The view shown is focused on the 5-strand and the 5-6 loop