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Under low-oxygen conditions, mitochondrial electron transport chain dysfunction and hypoxia-induced activation of oxidases [478] synergistically drive pathological ROS accumulation [479] that overwhelms cellular antioxidant defenses
FIGURE 3 In addition to the classical rotenone-sensitive NADH dehydrogenase, the electron transport chain of both amoebas additionally contains an alternative rotenone-insensitive NADH dehydrogenase (NDH-2)
[DOI] [PMC free article] [PubMed] [Google Scholar] Mao Q., Qin W
Clinical Validity of FoundationOne Liquid CDx for Detection of BRAFV600E in Colorectal Cancer
