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The neuroprotective treatment of AIS mainly targets ischemic cascades, such as mitochondrial dysfunction, oxidative stress injury, neuroinflammation, and programmed cell death processes including apoptosis, pyroptosis, and ferroptosis

In this setting, CD38 is expressed on several immunosuppressive cell types including regulatory T cells (Tregs), regulatory B cells (Bregs), myeloid-derived suppressor cells (MDSCs), and NK cell subsets [42]

Speak to a clinician before starting any vitamin ampoule programme , and have your B12 status reviewed with appropriate blood tests where applicable

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