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To further investigate the protein-protein interaction (PPI) network underlying the therapeutic mechanism, the shared target genes were uploaded to the STRING database for PPI network construction

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doi: 10.1016/j.omtn.2023.102066

In this situation, it can be challenging to demonstrate B12 deficiency even when there are typical symptoms (including neuropathy-like paraesthesia and numbness), as serum B12 concentrations may be just within, or sometimes above, the normal range due to the oral supplementation