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Additionally, TPO-Ab enhance pro-inflammatory cytokine responses to TPO in mononuclear cells (20), contributing to inflammation and extra-thyroidal diseases (49).Ott et al., demonstrated that elevated pre-operative TPO-Ab levels were significantly associated with fatigue, irritability, and reduced QoL in euthyroid patients undergoing surgery for benign goitre (18)

People who have the ABCC11 loss-of-function variant dont have the bacteria on their skin.[ref] Want to know more about the details

A Samanta TET Hughes VY Moiseenkova-Bell 2018 Transient Receptor Potential (TRP) Channels Subcell Biochem 87:141-165 Sideris A, Doan LV
