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NSAIDS should be discontinued 24 hr before the administration of methotrexate in order to avoid increased plasma concentration of the cytotoxic agent

[DOI] [PubMed] [Google Scholar] 23.Sikiric P., Seiwerth S., Rucman R., Turkovic B., Rokotov D.S., Brcic L., Sever M., Klicek R., Radic B., Drmic D., et al
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Store the reconstituted solution in the refrigerator (2C to 8C) and use it within the recommended time frame to ensure potency, following laboratory guidelines throughout the process