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Glutathione can eliminate these harmful molecules, reduce DNA damage, and support intracellular repair mechanisms to maintain gene stability

Converting tanshinone IIA into its sodium sulfonate form (sodium tanshinone IIA sulfonate, STS) greatly increases polarity and bioavailability, and indeed STS is used interchangeably with tanshinone IIA in studies and has been approved in China as an injectable drug (Shao et al., 2024

The pathomechanisms, which are studied in the scope of clinical trials, are supported by the in vivo models

A flow rate of 0.5 mL/min was used for both the in-vitro synthesis of salsolinol and pVTA experiments with elution carried out using LC grade H 2 O (A) and 100% ACN (B), both acidified with 0.1% FA Different elution gradients were used