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Description
290292 Accumulating macrophages release cytokines and chemokines, including IL-1, IL-6, chemokine ligand 2 (CCL2), and TNF-, intensifying the inflammatory environment and aggravating nerve damage

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Thiamine was reported to improve the symptoms of chronic cluster headache in a case study, confirming its role in pain modulation [74]
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But it is also worth venturing into the town that has given its name to the tourist resort
