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Clinical Trial Data Weight Loss and Metabolic Endpoints Cagrilintide as monotherapy demonstrated 10.8% mean body weight reduction at 26 weeks in the Phase 2 REWIND trial, with gastrointestinal adverse events (nausea, vomiting) reported in 42% of participants during dose escalation
Tumor-associated macrophages are important mediators of tumorigenesis and are also form reciprocal loops with CAFs
