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Big Potassium (BK) ion channels in biology, disease and possible targets for cancer immunotherapy
10.1016/j.tiv.2004.06.011 Toxicol
In many cancers, wild-type p53 is functionally inactivated through binding of negative regulators (e.g., MDM2/MDMX) to its transactivation domain (TAD), making disruption of these interactions a key therapeutic strategy
C., Norman, J
