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Glutathione is a tripeptide, consisting of three amino acids, that is produced in the liver and plays a critical role in protecting the body from oxidative stress

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During differentiation, DRP1 activity plays a crucial mechanism in cellular lineage patterning for cardiac, muscle, and neuronal cells ( To summarize, iPSCs utilize glycolysis as their main pathway for energy production, and primarily dependent on fatty acid or amino acid precursors for their metabolic demands to achieve unrestrained expansion

In drawing on studies that extend from clinical epidemiology, through genetics, pharmacotherapy and animal models, to cell biology and biochemistry, we have aimed to provide a comprehensible and accessible narrative, although this comes at the expense of a fully comprehensive and systematic (and inevitably longer) analysis