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While its been studied for multiple things from tendon repair to gut healing, one of the most exciting applications is for joint healthspecifically arthritis

Melatonin Suppresses Inflammation and Blood-brain Barrier Disruption in Rats with Vascular Dementia Possibly by Activating the SIRT1/PGC-1/PPAR Signaling Pathway

doi: 10.1007/s11064-009-0069-7

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