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The generation of oxidative stress, characterized by an imbalance between the production of free radicals and the bodys antioxidant defenses, can lead to the activation and perpetuation of autoimmune responses [7]

Results are cumulative each session builds on the previous one

Study selection Study inclusion criteria were as follows: patients diagnosed with IC/BPS, interventions included relevant treatments, comparisons were specified as control or placebo, outcomes were mean differences for individual symptoms (pain, frequency, urgency and nocturia) and structured questionnaires (ICPI, ICSI, PUF and FBV) using an RCT study design