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These can include, but are not limited to, pain, redness, or swelling at the place of injection

All these interesting results indicate that although TME-modulating treatment with H-MnO 2 -PEG/C&D could reverse the immunosuppressive microenvironment inside tumors and trigger CTL-mediated anti-tumor immunities, the PD-L1 blockade could further potentiate the generation of tumor antigen-specific CTL effector cells, which are then migrated into the distant tumors to kill tumor cells there

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Samiec PS, Drews-Botsch C, Flagg EW, Kurtz JC, Sternberg P, Reed RL, Jones DP: Glutathione in human plasma: decline in association with aging, age-related macular degeneration, and diabetes