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Sermorelin for growth hormone deficiency treatment

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using the Broad Institutes Connectivity Map (cMap), a compendium of transcriptional responses to compounds, identified GHK as the most active of 1309 bioactive substances, uniquely capable of reversing the expression of 54 genes in a metastatic-prone signature for aggressive early stage mismatch-repair colorectal cancer

The receptor is then trafficked to clathrin-coated vesicles (CCVs) and internalized via endocytosis
