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However, increased ROS production in PD is closely linked to mitochondrial dysfunction (Weng et al., 2018) The discovery that mutations in the genes encoding proteins like -syn, parkin, DJ-1, or PINK are associated with familial types of PD raises the question of how oxidative stress and dopamine (DA) cell damage are related to mitochondrial dysfunction (Gonchar et al., 2019

Ruvolo P, Qiu Y, Coombes K, Zhang N, Ruvolo V, Konopleva M, Andreeff M , Kornblau S

[DOI] [PMC free article] [PubMed] [Google Scholar] 4.Verster J.C., Scholey A., van de Loo A.J.A.E., Benson S., Stock A.-K