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Products containing bitter melon, cinnamon, fenugreek, or other herbs that may affect glucose metabolism or gastric motility should be discussed with the prescribing provider, as additive effects with tirzepatide are possible

B12 supplementation is appropriate for individuals with confirmed deficiency, vegans, older adults, those with malabsorption disorders, people who have had bariatric surgery, and those on long-term medications such as metformin or proton pump inhibitors

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