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335 As documented in this section and Table 3, antineoplastic agents/methods with ROS-inducing potential and their ROS-mediated antitumor mechanismscompiled from sources including the FDA database (www.fda.gov), ClinicalTrials.gov, and DrugBank ( diverse mechanisms of action ranging from metabolic interference to direct oxidative damage

As an antioxidant enzyme, GPx1 modulates the balance between necessary and harmful levels of reactive oxygen species

The sensitivity of the modified GPx-Tiron method was evaluated by calculating the limits of quantification (LOQ) and limits of detection (LOD)
