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If left untreated, PA can lead to joint deformity, reduced mobility, and chronic pain
Cycle breaks become mandatory if you have been on protocol for 12+ weeks continuously or if response has dropped significantly despite dose adjustment
Researchers studying mucosal integrity, gastric ulcer models, and intestinal permeability have used it to investigate cellular protection mechanisms in laboratory settings
Loren Pickart isolated it in 1973 while studying age-related changes in liver cell function
