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Another study demonstrated that the supplement decreased the amount of apoptotic-related mediators such as caspase 3,9, cytochrome C and protected L-glutamate induced cell death in PC12 cells through the Bcl-2/Bax apoptotic pathway [9698]

doi: 10.4103/2229-3485.179435

Dihydrolipoamide dehydrogenase (E3) deficiency (OMIM# 246900) The DLD gene encodes dihydrolipoamide dehydrogenase (also known as E3), a common flavoprotein shared by three mitochondrial -ketoacid dehydrogenase multi-enzyme complexes: pyruvate dehydrogenase complex (PDHC), -ketoglutarate dehydrogenase complex, and branched-chain -keto acid dehydrogenase complex

All eligible TriNetX patients were included