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[37] [38] I is moved across the apical membrane into the colloid of the follicle by pendrin
i.e., when wakefulness occurs at a time the internal circadian clock is promoting sleep and/or when sleep occurs at a time when the internal clock is promoting wakefulness (Baron and Reid, 2014
Braidy N, Liu Y
Each potentiates the others effects and may further establish vicious feedback in IR injury 13,14
