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10.3389/fped.2019.00246 Front Pediatr

doi: 10.1016/j.apsusc.2017.04.092
Acute application of the metal decreased AMPA evoked currents (IC 50 = 22.9 M) compared to neurons treated with AMPA alone, in addition to decreasing synaptic activity

Curcumin has shown inhibition of 50% HDAC activity at a very high concentration of 500 M in HeLa nuclear extracts (with IC50 value of 115 M)
