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Therefore, investigating endogenous HDAC expression and regulation within specific cell types during aging and AD is essential to elucidate their distinct roles and influence on cognitive processes in physiological and pathological states

MECHANISMS OF VITAMIN B12 DEFICIENCY IN PATIENTS TREATED WITH METFORMIN The underlying mechanisms implicated in reduced vitamin B12 levels secondary to metformin use remain unclear

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29 There is also a lack of data on the long-term benefit of oral therapy when patients do not take daily doses