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ROS can promote the oxidative damage of DNA and free deoxyribonucleoside triphosphates, leading to cell death

It is twice as common in women than in men, hence, it was relabeled early on as stiff-person syndrome instead of the original stiff-man syndrome. Patients typically present with muscle spasms and stiffness, concurrently in the thoracolumbar paraspinal and abdominal muscles, resulting in difficulties turning and bending (28

Low ferritin levels indicate a higher survival rate

doi: 10.1093/advances/nmx001 398
