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Overall, the observed AEs in the 2-year follow-up were of grade 1 or 2, with the exception of an MS relapse that occurred 78 weeks after the transplantation and led to a clinical worsening (EDSS from 6.5 to 7.5), due to a new enhancing lesion, followed by complete recovery after steroid treatment and physiotherapy

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QBT improved cognitive dysfunction in rats with vascular dementia by regulating the Nrf2/xCT/GPX4 and NLRP3/Caspase-1/GSDMD pathways to inhibit ferroptosis and pyroptosis of neurons